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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6641318a29e46c6a1c23a862aa2ead0b034072ff57fcff4e01a1aee138aa9f60' 
  AND token = 'DHUhwCDDkakSWGJnrLxVQYyC7FGtwAeSRFDkehsBraU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}