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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d431aeb868228f7e875b90429f244d3d416dd36a0bba5ee074982a7c065fc0' 
  AND token = 'TNscOnIXave4tYha/yjrfy3v6KHkBLto3uFrY1I8gQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}