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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f54c64727e199a9b64b31f48435d16a45b41252d53500f7586e5c4b416efa35e' 
  AND token = 'tAFLqtox1uj/lBOyHTz61XUYdjAN/SROc8TeaQAKcvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}