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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abde852b23c1f0e61dd5e14d28b5970e514e7de4ec0d2d1d250e632f29f1381f' 
  AND token = 'crURaNDbnAU/YT8aOmWJ15+wox6sgN4C59e2yUmXRVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}