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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b487908be5c8168a10c48cd2779056be8cd574f584d30b7afdda9422eed6f23' 
  AND token = 'DnCpvastckKhzfvLyM9jMzMuVs8McotS9a3Z1mS4Iqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}