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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d0b165d7ae32ec500060e74fb6bb202cafecfbcca52ae14a1097061e945f007' 
  AND token = '81OXqGrClp6pKOoJJvbwqBYQVKiKbpm8G847LA4s9ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}