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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2854300d9a943ed4c8a53c0b117410df1b6561773774339f15eba5ee704e09f3' 
  AND token = 'O1XrzRvsot/51HN7M3gDH68wK4b/ki1xlRy8jmQmkmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}