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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3507d7ebaa7627fbda59e4977b27dc8d712d3d59bc08b16e9cb245ec413ec43' 
  AND token = 'uk6pmxjjtTlTCCHBuVj2oTZItDOOcU214psakKQmZLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}