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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d8b19f6e1aaa652cf6ef69ffd81f06372ceaa446f4d2ba06fc37336f87bd734' 
  AND token = 'MLN4Cw+vOee+35bUzu0UX0SM+kj9yFPV4DP0NZ9wa68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}