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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f4df6020c25fa5ab3cc6bcd3c077960d4a69c62755f6256eb4b9fe333fd47b7' 
  AND token = '4o/9b1ECA1qAwFseUjkMs3tU0HWw1fDrM6jS0FnPVMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}