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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e4de9046a6dca650174c9749d61fb215764fa6b351bc81f69a3f2ddc0aaa058' 
  AND token = 'Mf+m89qhbEdmZMdqFnwcK6jE02wBLPqVBRAvqdimyvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}