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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37819f1c1177d5310fb49e12cdb2298d89cb5e8649c3cd3f315500498c76f7c0' 
  AND token = 'q8tbF8m6IvlxYuaqkMWBIdSs/suTROo2aWkagpx2zE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}