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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ff107991296db39aee2f5e9fd9903f0029e2189f086cd8b2c786723f4d021a' 
  AND token = 'hoRluf7W21qgOI+siwd0onVCPcJVspjEOITg5JbpbXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}