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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '847bd8a9fc0f36883a49666b5fc2aaa46d94f17c0da284015250e8a17dc53011' 
  AND token = 'n38nz1iALuLyYbj7S7IPSgn0OwIi4Pw9MaDAabwZvjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}