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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc1cfdd6706bb1e4d06841f91e234f1477ee9d4ca0a69a798cf2a12d423da391' 
  AND token = 'mjl22NZnLI3If++bXwsm/DmmRRhyeIi+1mhM2bw6pU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}