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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e0858a80f9c34a654cac08aa8b3b59876c4a7b34325c223845b1580c02f4548' 
  AND token = 'zsmUa0o01mYmQhZ6eQ86dtx/c7VS+S1QIqS8HzlU3PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}