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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387cf33b10916ed6663b970b03fe3e10dc7f98c36a01a1538ed1ff28452f68d2' 
  AND token = 'oS6egHtL7XmulFSYb8+uaES//r9PnKG27epYkp1RlLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}