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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86ce1634af20fb60857a80840d211c6fa5426239ded3f0c15a35ee263e9d72c1' 
  AND token = 'WZR6qxd2pL4IAL/s0zhiIT0jutq+MjCIEL1d99LgFug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}