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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c635e1c17a203b7aa5fd80571e2d2a74d37cc9907a45fb4456d067ce7a1b468' 
  AND token = 'yet1p/I5VzgK63A8iZS3fQTST3juAeWqcpC2ZjlrhRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}