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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12211280d38a9a7da40af0b16b16c17b464184b48661c40e155c47d4dd001c2f' 
  AND token = 'hO/xGkRfozRgR/KO/ffDMKuEluNNOP35ahiHEn+j5V4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}