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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18628f42f549f621d153484b7d47c2f277e9d0cd01c8b94635075240526a0e7c' 
  AND token = 'TAsozwdA7kMw0fWIsrJZcyAiu9ONSg/HPE2UbjZIMKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}