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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0c4f33740d416fde18c8208c1bcc92cc270344265daab8e8f64392cef216646' 
  AND token = 'f3z1NAZ7VfqbrarPtVX8e+4DkB+giyK7jrElozomeGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}