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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd26c0cb16fc38558e8d635e78f53ea7cdde3e805335a8cd6ef51d24a545ef1b0' 
  AND token = 'MqEP2EcmGr7hh6SjB9uAMU9+uyp+6xr8oZfB0mDWmTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}