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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219d9cad352ac5a7e68edfc60c25ba7655377d0805ad01341b5513712a02c73d' 
  AND token = '1jqcCZ5NItx5RQrb316kVjCwkrvzlj6XRx/Zik8flY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}