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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b5094b56fa1fac505e8aa0efc88de9625deaa1ffe8f9c22a05e54581f189966' 
  AND token = 'F83JyuZ6NDlJU1qeYdCKK+LuVlkm/Ya2ENqjlH8VHBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}