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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed24096d5f96b6a9c809a01d9466b23ab04c117a97f9a1396f2d502b6694c9a' 
  AND token = 'hmtfBQNkbNUC4xFwNAU8xltCdy4Yt6jd61LFOMQF5X8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}