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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18fc228f087fae96780bebab5e5a6e8969f459731b5de1c5676558841af0dcfa' 
  AND token = '600EOMEBH4gyShcqMJdHqYxot7j/qxaldA4pM0Z1SZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}