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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd64e3daebc6720037748f3d4e2c4439f1254d5b9bae5822c302cbb875649e669' 
  AND token = 'd4AMvp3ax9ood12YDTNLNy2xmLyDvPpVKufEK4NXgqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}