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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc2046e2ee4781ce0b4a03c038fbbb4b56bbb7e69b3041ee4d113548ffd721dc' 
  AND token = 'H9SyjJiS/2MIMBwwekKV7/72YkHGByq7lBwUbBlqpDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}