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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165be1696387dc5bf1c1a2e9f38ce6cc727d95b05d5d34c82e9e440c12186cf0' 
  AND token = 'kYdF+0wd2GtUrp6LoZyl5R5lDWzuAtkyK8dj1L3lY5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}