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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f4882de2b475e5f4cecc5263f8e3cfa6081b04a8ec35b4d532b4f33e9a8705' 
  AND token = 'j8ibdh5VZX5+Pw4f7TvvB1AEQWiWVwkMe8zIxB9/nss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}