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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8af281bf53df2f36596dc3b4206184bcf4a98728df63584b316cd63b6cff627' 
  AND token = 'S2N05xxfcn+n2Rnvr0c1IynwkmOic639S2VEv2xFeq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}