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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dd25596b18112f5a40d4d79af6e454a056484eb178e006435c023f700856993' 
  AND token = 'z3gG+DHs/GJCi7ivOEtVy786e/rTsWelziKPwiwkipA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}