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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24cd5ad27dff07c1cbeb46ece4a58bba9c0527cfc5d72a479ad2e346625727e7' 
  AND token = 'aCwXzuQ/M6jx3Pd15GbvDUUYPUqoek275lGEiQ3jN7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}