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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353304c588e9807bba84376eec3c8cbde407f2ba16af6aa23f6052fa172feaa5' 
  AND token = 'X7n7ReEzdd6+PkpybJ5YLD4NT0Ll13xN97Rz5dKHdPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}