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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d1239dd66e600c92e08768cbdf62f1881b6d7a3af3e1b4d5b81a531d097401b' 
  AND token = '7zZylP89zXaB3PJy7n+802EB5OfheItpbRJg8QmF38s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}