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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782f69a1efe28d35bf762b61f846f43f23ddfadda9fe5a6da1a41b14df86ce0c' 
  AND token = 'S5VmFN14wYPd5l0XtEjfmCgAvoXCZvhhUnFhFXQlv7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}