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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2941029350f3b35f23e8709d266fff52b488c0ac427fff489b525b299b972023' 
  AND token = 'YIjdT6tZS7MBdFuv57nSbsgPB0TJMZAGt0c0DfJ1th4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}