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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b3b25c53a514a6646a35deac33c641f031811bb62e272e1f2b069bdccc2ae5b' 
  AND token = 'gLvubxCMX6A2a8UykJS6I2IwJAS/R/W7kmZ1XrsQsc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}