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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9553a09f4dd92728a8fe2a2fc9d1896fbaf319bca3db7f054446e27250a012d0' 
  AND token = 'zx+AMecoiz9LCtsn2tCK0qo1JOScBc2Z6JxQrWYHYOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}