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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '515778962654a5437b45253f20214f03c11e210fd4eae2298be80ccaaefa6cc2' 
  AND token = 'NNXSk4Vl2IjHcRH0/ApOKITLvXISxCb12DQmRwgDDjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}