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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22403e53963c83ba6ac6a3eb5e7cc638f6c929c16358c17d4b3250e3dc651e36' 
  AND token = 'GG5NKq/iciLexiwb2hmY82ytSjuuifxXQKzzI9BxN7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}