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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e8467aedbd7e5d627f4ac518c27aab1c62d097a92b8b163e33c2474c7b059b4' 
  AND token = 'AcG9v0p/E1HaASywXHaCLcezu5zfZtDRK/G1KgOm0Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}