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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2b55a38b812f780443d6a948f2effe1a2fe29b3ed7184794121716bd0ecb125' 
  AND token = 'l/bQvkISWAZyfwgQDAlIQMwih9IbruvoJv0HVINO+0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}