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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c5b3dc85e030fffd4b9f905ffe5dcd0f32cdde403b36671859c054569c0db7a' 
  AND token = '+NGT5HUY5l5TGdQrvPY2hAoQFhBtMTTpq9e9aMeAwHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}