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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '557194246d2396356a56c5a2ccf503a90f8ea6f32f41781807a27ba920fd1e4c' 
  AND token = 'zXX9hDz1dLpm9HK+wdSX/xS0Fn9/3OYCmtCl72peXXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}