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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bd8539b49db1958e445dee477e26d001b58db8e69146d64d1f17947c7bdb442' 
  AND token = 'Tt5H14L6N4EJCic8VzDQU0CyIM3A1/mom/ZVacsePDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}