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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd395df71bf2c7a117ea9ca9f84d5f1c68db910d00d9bcbef2600be84e6a2f74d' 
  AND token = 'lNohM4SS4zHF8QlLSedvX46C2vepX6LVsjn62MrRHhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}