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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '363ab1927bde191b94348b380d80ff52d13d263d24b5d16a5369e8e6049b974f' 
  AND token = 'o8776Fol8nJP4IRgOkADtHfIk+pWeu9MW1mCNUMZNpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}