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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e8a8e71c5a514e3c0e3e51324056a66a7b561e9fbcbcc504168e57e922b5816' 
  AND token = 'cm4n6Sl7dViYrh0H+3naXoZfZp+U+1w4sMAXfpKWYxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}